Endocrine Abstracts

Polycystic ovary syndrome (PCOS) is a characterized by hyperandrogenism and irregular menses and is associated with insulin resistance, type 2 diabetes and obesity. While there is a strong genetic component to PCOS, candidate gene analyses and genome wide association studies (GWAS) have identified only a handful of replicated PCOS susceptibility loci. Therefore, we employed a candidate pathway approach to identify additional PCOS susceptibility loci. This approach is more comp...